Bio-Filler Wakefield
Natural regenerative volume using your own platelet-rich fibrin
Bio-Filler is an advanced regenerative injectable treatment that uses platelet-rich fibrin from your own blood sample to support subtle volume, improve skin quality and encourage collagen production over time.
At Empire Medical Aesthetics & Skin, treatment is consultation-led and medically focused, with a personalised plan designed around your skin, anatomy and treatment goals.
Medical-led clinic
Treatment planned with clinical assessment and safety in mind.
Natural regenerative approach
Uses platelet-rich fibrin from your own blood sample.
Subtle, gradual results
Designed for natural-looking rejuvenation over time.
Consultation required
Suitability is assessed before treatment.
What is Bio-Filler?
Bio-Filler is a natural autologous treatment, meaning it is created from your own blood sample. The sample is processed to separate platelet-rich fibrin, which contains platelets, growth factors and a fibrin matrix.
This fibrin matrix acts as a natural scaffold within the tissue, supporting gradual rejuvenation, collagen stimulation and soft tissue quality.
Unlike traditional dermal filler, Bio-Filler does not use hyaluronic acid or synthetic filler product. Instead, it works with your own biology to improve skin quality and support subtle natural volume over time.
A natural regenerative option for suitable clients who want softer, fresher-looking rejuvenation rather than dramatic filler-style volume.
Subtle natural volume
Supports soft tissue quality without an overfilled appearance.
Fine line softening
May help soften fine lines, crepiness and early skin laxity in suitable areas.
Benefits of Bio-Filler
Bio-Filler is ideal for clients who want a refreshed, rested and natural-looking result while also supporting long-term skin quality.
Improved skin quality
Helps improve the appearance of texture, hydration and overall skin vitality.
Under-eye support
Can be suitable for mild under-eye hollowing, thinning skin or tired-looking eyes.
Collagen stimulation
Encourages gradual regenerative improvement over time.
Uses your own platelet-rich fibrin
A natural treatment created from your own blood sample.
What areas can Bio-Filler treat?
Bio-Filler can be used to support natural facial rejuvenation in carefully selected areas. The most suitable approach depends on your anatomy, skin quality, medical history and treatment goals.
Under-eyes / tear trough
For mild hollowing, thinning skin or tired-looking eyes.
Mid-face soft volume loss
For subtle support and skin quality improvement.
Marionette area
For lower-face soft tissue support.
Crepey or thinning skin
For skin that looks thin, fragile or lacking firmness.
Fine lines around the eyes
For delicate crepey skin and early lines.
Nasolabial area
For softening and regenerative support.
Perioral lines
For fine lines around the mouth.
General facial rejuvenation
For clients wanting an overall fresher appearance.
Bio-Filler vs dermal filler
Bio-Filler is not the same as traditional dermal filler.
Dermal filler is usually used when a client wants more immediate structure, contour or defined volume. Bio-Filler works more gradually by supporting collagen stimulation, tissue regeneration and softer natural volume.
This makes Bio-Filler a good option for clients looking for a natural regenerative result. However, it may not be suitable for clients wanting significant facial contouring, strong cheek projection or immediate filler-style volume.
Bio-Filler
Best for: skin quality, subtle volume and collagen support.
Result style: gradual, natural and soft.
Dermal Filler
Best for: structure, contour and defined volume.
Result style: more immediate and volumising.
Polynucleotides
Best for: skin quality, hydration, repair and regeneration.
Result style: gradual skin improvement.
During your consultation, we will discuss whether Bio-Filler, dermal filler, polynucleotides, skin boosters or another treatment would be most appropriate for your goals.
1. Consultation and facial assessment
We discuss your concerns, treatment goals and assess your facial anatomy.
4. PRF preparation
The sample is processed to separate the platelet-rich fibrin.
What happens during Bio-Filler treatment?
Clinical photographs may be taken as part of your medical records and insurance documentation.
Your appointment begins with a consultation and suitability assessment. If treatment is appropriate, a small blood sample is taken and processed to prepare the platelet-rich fibrin before it is carefully injected into the selected areas.
2. Medical history review
Your medical history, medication, allergies and suitability are checked before treatment.
5. Treatment performed
The PRF is carefully injected into the agreed treatment areas.
3. Blood sample taken
A small blood sample is collected for preparation of the PRF.
6. Aftercare advice
You will receive clear aftercare instructions to support healing and reduce avoidable risks.
When will I see results?
Bio-Filler results are progressive rather than instant. Some clients notice early improvement in hydration, texture and soft tissue support, while regenerative changes continue to develop over time.
2–4 weeks
Early improvement may begin.
6–8 weeks
More visible rejuvenation often develops.
Up to 12 weeks
Collagen stimulation and tissue improvement may continue.
6–9 months
Maintenance may be recommended.
Results depend on your age, skin quality, general health, lifestyle and treatment area.
1 Area
£395
Focused treatment for one area, such as under-eyes, fine lines, perioral lines, nasolabial area or marionette area.
PRF Bio-Filler pricing
Bio-Filler is priced by treatment area rather than by ml. This is because the treatment is created from your own blood sample and planned around your anatomy, skin quality and treatment goals.
Course of 3 treatments
1 Area — £1,050
2 Areas — £1,350
3 Areas / Full Face — £1,750
Most clients benefit from 2–3 treatments spaced 4–6 weeks apart. Your final treatment plan and pricing will be confirmed during consultation.
2 Areas
£495
A more balanced regenerative treatment plan, such as under-eyes and mid-face, or lower-face rejuvenation.
3 Areas / Full Face
£650
A wider facial rejuvenation treatment to support skin quality, subtle volume and collagen stimulation across multiple areas.
May be suitable for clients who want:
- Subtle, natural-looking rejuvenation
- Mild under-eye support
- Fine line or crepey skin improvement
- Skin quality improvement
- A regenerative injectable option
- Gradual rather than dramatic results
Is Bio-Filler suitable for me?
Possible side effects include redness, swelling, bruising, tenderness, temporary lumpiness, infection, asymmetry, unsatisfactory result and rare vascular complications associated with injectable treatments.
Bio-Filler uses your own blood components, which may reduce the risk of allergic reaction compared with some synthetic products. However, it is still an injectable medical-aesthetic procedure and carries potential risks.
Suitability will always be assessed during consultation before treatment is carried out.
May not be suitable if you:
- Are pregnant or breastfeeding
- Have an active infection
- Have been recently unwell
- Are currently taking antibiotics
- Have certain blood disorders
- Take some anticoagulant medication
- Have active skin inflammation in the treatment area
- Have unrealistic expectations of treatment
Medical-led consultations
Treatment begins with assessment, suitability and honest advice.
Natural-looking results
Our focus is subtle, balanced improvement rather than overfilled or artificial results.
Why choose Empire Medical Aesthetics & Skin?
Empire Medical Aesthetics & Skin is a medical-led clinic in Wakefield specialising in natural-looking aesthetics, regenerative skin treatments and personalised treatment planning.
Safety-first approach
Your treatment plan is based on anatomy, medical history and clinical need.
Bespoke treatment plans
Your treatment is tailored to your skin, goals and facial structure.
Regenerative skin expertise
We offer advanced treatments designed to support skin quality and long-term rejuvenation.
Clear aftercare
You will be given professional aftercare advice following treatment.
Bio-Filler FAQ
Frequently asked questions
Common questions about our regenerative Bio-Filler treatment using your own platelet-rich fibrin.